•  Over 25,000 bioactive molecules in stock

•  High purity & competitive prices

•  Target 375 key proteins in 20+ signaling pathways

•  Data sheet with detailed biological information

•  Quality reports (LC/MS, NMR and HPLC) for each product

•  Delivery within 24 hours

•  Release more than 500 of the newest biochemicals per month

• Complement System

AMY-101 acetate

AMY-101 acetate (Cp40 acetate), a peptidic inhibitor of the central complement component C3 (K_D = 0.5 nM), inhibits naturally occurring periodontitis in non-human primates (NHPs). AMY-101 acetate (Cp40 acetate) exhibits a favorable anti-inflammatory activity in models with COVID-19 severe pneumonia with systemic hyper inflammation.

• AMPK Activator

IM156

CAS No. : 1422365-94-3

IM156 (HL156A; HL271 acetate), a chemical derivative of metformin (HY-B0627), is a potent AMPK activator that increases AMPK phosphorylation. IM156 attenuates aging-associated cognitive impairment in animal model. IM156 is a potent oxidative phosphorylation (OXPHOS) inhibitor which can be used for the research of solid tumors.

• CDK Inhibitor

K00546

CAS No. : 443798-47-8

K00546 is a potent CDK1 and CDK2 inhibitor with IC₅₀s of 0.6 nM and 0.5 nM for CDK1/cyclin B and CDK2/cyclin A, respectively. K00546 is also a potent CDC2-like kinase 1 (CLK1) and CLK3 inhibitor with IC₅₀s of 8.9 nM and 29.2 nM, respectively.

• Microtubule/Tubulin Inhibitor

Batabulin sodium

CAS No. : 195533-98-3

Batabulin sodium (T138067 sodium) is an antitumor agent, which binds covalently and selectively to a subset of the β-tubulin isotypes, thereby disrupting microtubule polymerization. Batabulin sodium affects cell morphology and leads to cell-cycle arrest ultimately induces apoptotic cell death.

• iGluR Antagonist

TCN 201

CAS No. : 852918-02-6

TCN 201 is a potent, selective and non-competitive antagonist of GluN1/GluN2A NMDA receptor, with a pIC₅₀ of 6.8. TCN 201 is selective for GluN1/GluN2A NMDA receptor over GluN1/GluN2B NMDA receptor (pIC₅₀<4.3).

Other New Products This Month

Infliximab (TNF Receptor)

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Phenidone (COX)

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Pramipexole (Dopamine Receptor)

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Ropivacaine (Sodium Channel)

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Loxoprofen (COX)

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CRT0044876 (DNA/RNA Synthesis)

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GI-530159 (Potassium Channel)

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Ganciclovir (CMV)

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Win 18446 (Aldehyde Dehydrogenase (ALDH))

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Gemigliptin (Dipeptidyl Peptidase) ...

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