THP-1 cells have been widely used in the research of monocyte and macrophage related mechanisms, signaling pathways, nutrient and drug transportation. It is an ideal tool for studying immunity and inflammation. |
The success rate of THP-1 is very low by conventional gene-editing methods. CRISPR/Cas9 technology is more simple and efficient.
CRISPR-U™,developed by Ubigene, is more efficient than general CRISPR/Cas9 in double-strand breaking, and CRISPR-U™ can greatly improve the efficiency of homologous recombination, easily achieve knockout (KO), point mutation (PM) and knockin (KI). |
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Ubigene Biosciences Co., Ltd.