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Alpha Synuclein: a Parkinson's Disease
Biomarker | |
Dear Researcher,
Aggregated
α-synuclein
and in particular it’s oligomeric form, is well known as the primary component
in Lewy body fibrils, and these fibrils are a classic pathology symptom of
Parkinsons’ Disease (Klatt et al., 2020). Both monomeric and oligomeric α-synuclein, can be
detected in a range of biological samples including, cerebrospinal fluid, blood
plasma, saliva and red blood cells (RBC).
However, finding an assay that measures accurate
amounts of α-synuclein from a specific biological sample is often challenging,
as described in a recent study. Klatt et al., (2020), noted
that not only is optimizing protein extraction important but employing an assay
that measures the accurate concentration of an analyte, such as α-synuclein from
RBC is vital.
Biosensis is
addressing the need for reliable and accurate quantification of α-synuclein with
it’s recently released RapidTM
ELISA Kit for this important target (BEK-2216).
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The Biosensis α-synuclein RapidTM ELISA Kit BEK-2216
features:
· Real
validation data on accurate quantification in human blood and CSF
· Low
intra- and inter-assay CVs of < 10%
· Complete
kit with precise instructions
· Fast
(< 4 hours) and reliable assay performance
· Excellent
batch-to-batch consistency