Polio-related Antigens and Antibodies Accelarate Your Vaccine Development
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Antigens and Antibodies for
Poliovirus
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Recently, polioviruses
were detected in wastewater samples across various counties in New York,
suggesting a community spread among unvaccinated groups. Polio, or
poliomyelitis, is a disease caused by the poliovirus. There are three
serotypes of polioviruses, namely wild poliovirus types 1, 2, and 3. Polio is
a contagious disease that spreads from person to person and can infect one's
spinal cord, causing paralysis. Nevertheless, vaccination is so far the most
effective way to prevent polio infection.
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Polio may be detected by
the discovery of polioviruses within stool specimens or diagnosed through
testing for neutralizing antibodies against polioviruses in blood samples.
Meanwhile, ELISA-based serology is a sensitive and specific method for
determining antibodies from infection with vaccines or wild viruses. Creative
Diagnostics offers polio-related antigens and antibodies for ELISA assay
development suitable for assessing the efficacy of vaccines and qualifying
and/or standardizing vaccine batches and protocols.
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Polio-related
Antigens, Antibodies, and ELISA Kits
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Please
note that ALL products are intended for research use only; Not for diagnostic
or clinical use.
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Resources
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Poliovirus
Antigens
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Polioviruses constitute three
closely related serotypes (types 1, 2, and 3) within a large group of
enteroviruses C, each of which can cause poliomyelitis. Poliomyelitis is
highly contagious and spreads by the fecal-oral and oral-oral routes.
Humans are the only natural hosts of poliovirus.
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Learn more
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Adeno-Associated Virus (AAV)
Antigens
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Adeno-associated virus (AAV) is
one of the most actively investigated gene therapy vehicles. It was
initially discovered as a contaminant of adenovirus preparations, hence
the name. Briefly, AAV is a protein shell surrounding and protecting a
small, single-stranded DNA genome of approximately 4.8 kilobases (kb).
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Learn more
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