News & Promotions

Provide total solutions for Life Science applications together with global partners. We are constantly striving to be more
connected, forward-looking and customer-focused to deliver best results.

News & Promotions


[ MCE (MedChemExpress) ] New Products_New Small Molecules for January 2020

관리자 2020.01.06 21:28 조회 870 추천 11


MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel bioactive compounds, dye reagents, peptides and natural compounds for laboratory and scientific use.
•  Over 15,000 bioactive molecules in stock •  High purity & competitive prices
•  Target 375 key proteins in 20 signaling pathways •  Data sheet with detailed biological information
•  Quality reports (LC/MS, NMR and HPLC) for each product •  Delivery within 24 hours
•  Release more than 500 of the newest biochemicals per month  
• MAPKAPK2 (MK2) Inhibitor

CAS No. : 1276121-88-0

PF-3644022 is a potent, selective, orally active and ATP-competitive MAPKAPK2 (MK2) inhibitor with an IC50 of 5.2 nM and a Ki of 3 nM. PF-3644022 also inhibits MK3 and p38 regulated/activated kinase (PRAK) with IC50s of 53 nM and 5.0 nM, respectively. PF-3644022 potently inhibits TNFα production and has anti-inflammatory effect.

• Protease-Activated Receptor (PAR) Antagonist
SCH79797 dihydrochloride

CAS No. : 1216720-69-2

SCH79797 dihydrochloride is a highly potent, selective nonpeptide protease activated receptor 1 (PAR1) antagonist with an IC50 of 70 nM.

• NO Synthase Inhibitor
AR-C102222 hydrochloride 

CAS No. : 1781934-50-6

AR-C102222 hydrochloride is a potent, competitive, orally active and highly selective inducible nitric oxide synthase (iNOS) inhibitor, with an IC50 of 37 nM. AR-C102222 hydrochloride has antinociception and anti-inflammatory activity.

• Motilin Receptor Antagonist

CAS No. : 287206-61-5

MA-2029 is a selective, orally active, and competitive motilin receptor antagonist (IC50=4.9 nM).

• CCR Antagonist

CAS No. : 1784252-84-1

C-021 dihydrochloride is a potent CC chemokine receptor-4 (CCR4) antagonist. C-021 dihydrochloride potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM, respectively.

Compound Screening Libraries
Get Your Inhibitor Sample
Cell Signaling Pathway

Other New Products This Month

CY 208-243 (Dopamine Receptor) | NS5806 (Potassium Channel) | FPA-124 (Akt) |
PF-06882961 (Glucagon Receptor) | NTP42 (Prostaglandin Receptor) | Mifobate (PPAR) |
PF-00356231 hydrochloride (MMP) | GR 103691 (Dopamine Receptor) | Prinomastat (MMP) |
CYM 9484 (Neuropeptide Y Receptor) ...