Reagents for
Tetanus Vaccine Development
Tetanus,
also known as lockjaw, is a bacterial infection caused by Clostridium tetani and
characterized by muscle spasms. Clostridium
tetani produces
the tetanus neurotoxin (TeNT),
which is released as a single 150 kDa
polypeptide chain.
Unlike
most infectious diseases, naturally infected tetanus patients usually do not
develop immunity after recovery. Tetanus can be prevented by tetanus toxoid
vaccination. For children under seven years of age, tetanus vaccine is often
administered as a combined vaccine, the DPT/DTaP vaccine, which also includes
vaccines against diphtheria and pertussis. For adults and children over seven,
the Td (tetanus and diphtheria) or Tdap (tetanus, diphtheria, and acellular
pertussis) vaccine is commonly used.
Creative
Diagnostics provides immunological reagents including antibodies and antigens
to develop quantitative immunoassays for the detection of TeNT
in various species. Our ELISA test kits provide quantitative or qualitative in vitro
assays for antibodies against tetanus toxoid.
Performance
Tetanus
Antibodies
Antibody
pairs can be used in the development of sandwich ELISAs.
Anti-TeNT
MAbs
are highly specific to C. tetani.
Most
antibodies are validated for ELISA, WB, etc.
CABT-NS1533
effectively neutralizes TeNT.
Tetanus
Antigens
>80%
purity (SDS-PAGE), manufactured in large scale.
C.
tetani related native antigens and recombinant antigens expressed by E. coli or P. fluorescens are used for the detection of antibodies specific to
TeNT in assays including ELISA, WB and HA.
Tetanus
ELISA Kits
ELISA
test kits provide quantitative or qualitative in
vitro
assays for human, mouse, rat, rabbit and monkey IgG or IgM antibodies against
tetanus toxoid.
Contain
quality control antibodies and standards for accurate quantification.
Products Available
Tetanus
Antibodies
Cat. No.
|
Product Name
|
Host
|
Application
|
CABT-NS1652
|
Anti-C.
tetani Toxin (TeNT) Polyclonal Antibody
|
Rabbit
|
ELISA
(Cap)
|
CABT-NS1530
|
Anti-C.
tetani Toxin Monoclonal Antibody, Clone IZC 279-22
|
Mouse
|
ELISA
(Det)
|
DCABY-466
|
Anti-C.
tetani Toxin Monoclonal Antibody, Clone UfuI7
|
Mouse
|
ELISA,
FuncS, WB
|
CABT-NS1531
|
Anti-C.
tetani Toxin Monoclonal Antibody, Clone TetF4
|
Mouse
|
ELISA,
WB
|
CABT-NS1533
|
Anti-C.
tetani Toxin Monoclonal Antibody, Clone D124
|
Mouse
|
ELISA,
WB, Neut
|
CABT-NS1534
|
Anti-C.
tetani Toxoid (Tetanus Light Chain) Monoclonal Antibody, Clone 23D22
|
Mouse
|
ELISA,
WB
|
CABT-NS1535
|
Anti-C.
tetani Toxoid (Heavy Chain Fragment C) Monoclonal Antibody, Clone 29.2.8
|
Mouse
|
ELISA,
WB
|
CABT-NS1536
|
Anti-C.
tetani Toxoid (J558; 9A) Monoclonal Antibody, Clone 29.2.23.7
|
Mouse
|
ELISA,
WB
|
CABT-NS1537
|
Anti-C.
tetani Toxoid (VH J558; VK9A) Monoclonal Antibody, Clone 46G8
|
Mouse
|
ELISA,
WB
|
CABT-NS1538
|
Anti-C.
tetani Toxoid (VH Q52N; VK 12/13) Monoclonal Antibody, Clone 6F5
|
Mouse
|
ELISA,
WB
|
CABT-NS1540
|
Anti-C.
tetani Toxoid (VH 36-60; Vk 19/28) Monoclonal Antibody, Clone 92I21
|
Mouse
|
ELISA,
WB
|
CABT-NS1539
|
Anti-C.
tetani Toxoid (VH 36-60; VK4,5) Monoclonal Antibody, Clone 83C0
|
Mouse
|
ELISA,
WB
|
DPATB-H83287
|
Anti-C.
tetani Toxin Polyclonal Antibody
|
Rabbit
|
ELISA,
WB
|
DPAB0141
|
Anti-C.
tetani Toxoid Polyclonal Antibody
|
Goat
|
IEP
|
DMABT007
|
Anti-C.
tetani Toxoid Polyclonal Antibody
|
Goat
|
ELISA,
WB, IF, IP
|
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