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CAS No. : 1276121-88-0
PF-3644022 is a potent, selective, orally active and
ATP-competitive MAPKAPK2 (MK2) inhibitor with an
IC50 of 5.2 nM and a Ki of 3 nM. PF-3644022 also inhibits MK3 and
p38 regulated/activated kinase (PRAK) with IC50s of 53 nM and 5.0 nM, respectively.
PF-3644022 potently inhibits TNFα production and has anti-inflammatory effect.
No. : 1216720-69-2
dihydrochloride is a highly potent, selective nonpeptide protease activated
receptor 1 (PAR1) antagonist with an IC50 of
No. : 1781934-50-6
hydrochloride is a potent, competitive, orally active and highly selective
inducible nitric oxide synthase (iNOS) inhibitor, with an IC50 of 37 nM. AR-C102222 hydrochloride has
antinociception and anti-inflammatory activity.
No. : 287206-61-5
is a selective, orally active, and competitive motilin receptor
antagonist (IC50=4.9 nM).
No. : 1784252-84-1
dihydrochloride is a potent CC chemokine receptor-4 (CCR4) antagonist.
C-021 dihydrochloride potently inhibits functional chemotaxis in human and mouse
with IC50s of 140 nM and 39 nM,
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