Cytokine

They found that two cytokine levels were high; the IL-6 and TNF-a and those with higher levels of these two cytokines had more severe cases of COVID-19.

TNF-a

TNF-a was also a strong predictor of poor outcome.

Research

They found that two antiviral drugs were able to lower the cytokine levels; remesdivir and corticosteroid dexamethasone.